
Basic overview
Micronutrients
Vitamins are potent organic compounds which are found in small concentrations in foods. They perform specific and vital functions in the body chemistry.
They cannot be manufactured or synthesized by the organism
and their absence or improper absorption results in specific
deficiency disease. It is not possible to sustain life without
all the essential vitamins. In their natural state they are
found in minute quantities in organic foods.
Vitamins and minerals are needed in minute quantities by the
body but are essential for normal growth, muscle response,
health of the nervous system, digestion, production of hormones,
and metabolism of nutrients. Vitamins often act as coenzymes and
minerals are constituents of bones, teeth, soft tissue, muscles,
blood, and nerve cells. There are two kinds of vitamins:
water-soluble—B complex, C, the bioflavonoids, and beta
carotene—that are easily eliminated from the body; and fat
soluble—A, D, E, and K— that can accumulate if an excess is
ingested. Vitamins and minerals can be supplied by a varied diet
of fresh fruits and vegetables, whole grains, legumes, nuts and
seeds, fish, and low-fat animal
products.
Approximately 90% of the body’s vitamin A is stored in the liver
with small amounts deposited in the fatty tissues, lungs,
kidneys, and retinas. Under stressful conditions the body uses
this reserve supply if it doesn’t receiving enough of the
vitamin from the diet. The liver needs a sufficient supply of
zinc in order to mobilize and release stored vitamin A into the
bloodstream.
VITAMINS
Vitamin A
Vitamin A is essential in the formation of visual purple, a
pigment found in the retina of the eye that is needed for vision
at night. Health and the resiliency against infection of the
outer skin, and internally of the mucous membranes that line the
respiratory, gastrointestinal, and urinary tracts as well as the
mouth, nose, and ears depend on vitamin A. The vitamin is an
antioxidant and may be important in preventing cancer of the
lungs and cervix in women. It helps cells reproduce normally.
Vitamin A is fat-soluble and can accumulate in the body becoming
toxic if more than 50,000 IU are ingested daily. Pregnant women
should not take more than 10,000 IU each day.
Approximately 90% of the body’s vitamin A is stored in the liver
with small amounts deposited in the fatty tissues, lungs,
kidneys, and retinas. Under stressful conditions the body uses
this reserve supply if it doesn’t receiving enough of the
vitamin from the diet. The liver needs a sufficient supply of
zinc in order to mobilize and release stored vitamin A into the
bloodstream. The liver converts beta carotene obtained
from foods into vitamin A. Carotene is nontoxic and along with
other carotenoids is an antioxidant and offers more protection
against cancer than vitamin A by itself. These other
phytochemicals include alpha carotene, lutein, lycopene,
zeaxanthin, and cryptoxanthin and are found in the red, yellow,
and orange pigments of fruits and vegetables.
B COMPLEX
Foods that are especially rich in one of the B vitamins will also contain several other members of the complex as their functions in the body are closely interrelated. The B vitamins are also made by bacteria in the intestinal tract. The complex is most important for the health of the nervous system. B vitamins have a role in the metabolism of carbohydrates, fats, and protein, and are essential for maintaining the muscle tone of the gastrointestinal tract and heart. The B vitamins are water-soluble. They are not stored in the body in any great quantity and need to be supplied daily by the diet. The need for the complex increases during chronic illnesses, stress, and when alcohol, tobacco, and recreational drugs are used. Taking a single B vitamin should be accompanied by the complex in order to avoid an imbalance or deficiency of the others.
Vitamin B1 (thiamine)
Mental efficiency, health, and a feeling of wellbeing are dependent on thiamine. It is required for nerve cells to function normally. It is essential for the formation in every cell of adenosine triphosphate (ATP), the energy fuel that the body runs on. The vitamin easily dissolves in water, is vulnerable to heat during cooking, and to baking soda and powder in baked goods. It is a component of the germ and bran of wheat, the husk of rice, and that portion of all grains that is commercially milled out to give the grain a lighter color and finer texture.
Vitamin B2 (riboflavin)
Riboflavin is a constituent of enzymes
involved in cell respiration. It is also necessary for the
maintenance of good vision and healthy skin. The vitamin helps
convert carbohydrates to ATP, the
energy fuel. It has a yellow pigment and colors the urine.
Vitamin B3 (niacin)
Niacin is a coenzyme involved in the metabolism of proteins,
fats, and carbohydrates. Besides its
presence in food, the vitamin is manufactured in the body from
the essential amino acid tryptophan. It is important for blood
circulation and reducing cholesterol levels in the blood. Large
doses cause a flushing of the skin as a result of the dilation
of blood vessels but the effect is not harmful. A form of
niacin, niacinamide, does not cause any skin sensations,
however, large doses can damage the liver and cause depression
in some people. The form inositol hexanicotinate lowers serum
cholesterol without harming the liver. Doses of the vitamin
should not exceed 1000 mg a day, unless under the supervision of
a physician. High doses of niacin should not be taken during
pregnancy, or in cases of ulcers, gout, diabetes, gallbladder or
liver diseases, or recent heart attack.
Vitamin B6 (pyridoxine)
Pyridoxine is extremely important in the development of the
nervous system. It helps process amino acids and is involved in
the production of serotonin, melatonin, and dopamine. The
vitamin has been used to reduce morning sickness during
pregnancy. A hormonal shift leading to PMS (premenstrual
syndrome) in women, and nerve compression injuries such as
carpal tunnel syndrome, have been helped by the vitamin. Because
of its role in fat metabolism, a deficiency is associated with
atherosclerosis. A lack of the vitamin can cause depression.
Oral contraceptives can create a pyridoxine
deficiency, and much of the vitamin is lost in the processing of
foods and is not one of the vitamins that is replaced in
so-called “enrichment.” Nerve damage has been observed in
individuals taking more than 300 mg a day.
Vitamin B12
Absorption of B12 depends on the presence in the stomach of the intrinsic factor, a mucoprotein enzyme. Autoimmune reactions in the body may either bind the intrinsic factor to prevent B12 absorption or prevent cellular ability to produce the enzyme. B12 is closely related to the activity of four amino acids, pantothenic acid, and vitamin C. It also helps iron function better in the body and aids folic acid in the synthesis of choline. It has a role in the production of DNA and RNA, which are the body’s genetic material, and in s-adenosyl-L-methionine (SAMe), a mood altering substance. The vitamin, along with folic acid, regulates homocysteine levels. Homocysteine is an amino acid which, in excess, is associated with heart disease, stroke, osteoporosis, and Alzheimer’s disease. The vitamin is found in meats, fish, eggs, and milk and is not provided in vegetarian diets. Sublingual and nasal forms are effective as supplements. The daily recommended dose is 2 to 3 mcg.
FOLIC ACID
Folic acid is involved in the duplication of chromosomes
during cell reproduction, a process that is accelerated during
pregnancy when new tissue is being formed. The vitamin is
important in preventing birth abnormalities such as neural tube
defect which involves poor brain and spinal cord development,
and mental disorders that may be obvious or may be subtle in
effect and not noticed at birth or in infancy but become evident
later in life. It can help in preventing cleft palate.
Folic acid regulates blood homocysteine levels, an amino acid
associated with risk of heart disease, strokes, osteoporosis,
and Alzheimer’s disease. It is necessary for the production of
the mood related substance SAMe. Birth control pills and diets
high in fat and refined carbohydrates can cause a folic acid
deficiency. The vitamin is easily destroyed by high
temperatures..
PANTOTHENIC ACID
There is a close correlation between pantothenic acid tissue levels and function of the adrenal glands. The adrenals are, for example, important in responding to stress. Pantothenic acid is a part of the energy cycle and the production of acetylcholine, a neurotransmitter. It is involved in cholesterol and hormone synthesis. The vitamin is widely available in almost all natural foods; however, food processing destroys substantial amounts. Fifty percent of pantothenic acid is lost in the milling of grains and 37% in meat during cooking.
BIOTIN, CHOLINE, INOSITOL, AND PABA
These vitamins have been isolated in foods and their chemical
structures identified as part of the B group, although the
activity of para amino benzoic acid (PABA) is quite different
from other B vitamins. Biotin acts as a coenzyme in the
metabolism of fats, carbohydrates, and protein. Prolonged use of
antibiotics and antiseizure medicines interfere with its
production. It is destroyed by raw egg white.
The vitamin strengthens brittle nails and lowers blood glucose
levels preventing diabetic neuropathy. Deficiency symptoms
include fatigue, lack of appetite, dermatitis, hair loss,
anemia, nausea, and depression. Choline and inositol are
constituents of lecithin and are primarily associated with the
use of fats and cholesterol in the body and for cell membrane
integrity. Choline is a component of acetylcholine,
a neurotransmitter in the brain, and has been helpful in
treating neurological and psychological disorders. Inositol is
also involved in nerve transmissions. Diabetics excrete the
vitamin at a rate greater than normal. PABA occurs in
combination with folic acid and plays an important role in
determining skin health, hair pigmentation, and health of the
intestines.
Vitamin C (ascorbic acid)
Vitamin C is necessary for the formation of collagen, the
connective tissue in skin, ligaments, and bones, and is
important for the healing of wounds. The vitamin aids in forming
red blood cells and preventing hemorrhaging and bleeding gums.
It maintains the activity of white blood cells which act as
bacteria fighters, but too high amounts of C reverses that
effect and white blood cells actually become less active.
Vitamin C acts as an inhibitor of histamine, a compound that is
released during allergic reactions.
Vitamin C has shown protective effects against heavy metal
exposure, pesticides, and food additives
such as nitrates which have been associated with cancer. The
vitamin is an antioxidant, protects LDL cholesterol from
oxidative damage, supports the immune system, and helps prevent
cancer. Recent studies have shown vitamin C affects nitric oxide
activity, which is important in the dilation of blood vessels
beneficial in preventing artery spasms leading to heart attacks
and in lowering blood pressure.2
Birth control pills and aspirin deplete the tissues of vitamin
C. Ingestion of above 100 mg at
one time results in decreased efficiency of absorption and an
increased rate of excretion of unmetabolized ascorbic acid.
Tissues reach saturation at 200 to 250 mg. Large doses may
inactivate
vitamin B12, have caused demineralization of bones in animals,
may prevent the absorption of
calcium, interfere with the absorption of copper, and result in
the formation of kidney stones.
The bioflavonoids are part of the C complex and enhance the
effectiveness of vitamin C. They
are important in increasing the strength of the capillaries and
regulating their permeability. Some act as antihistamines, have
antiviral, anticancer, and anti-inflammatory properties, and
protect LDL cholesterol from oxidative damage. Bioflavonoids are
categorized as isoflavones, anthocyanins, flavans, flavonols,
flavones, and flavanones. Subcategories include rutin,
hesperetin, eriodictyol, quercetin (in onions), quercetrin,
hesperidin, and genistein (in soy), and are found in the edible
portions of fruits and
vegetables and in the white segments of citrus fruits..
Vitamin D
Vitamin D is necessary for the absorption of calcium from the
intestinal tract reducing its urinary loss, and for the
assimilation of phosphorus which is required in bone formation.
The vitamin aids in the synthesis of enzymes in the mucous
membranes that are involved in the transport of calcium. When
the skin is exposed to ultraviolet radiation, vitamin D is
formed from a cholesterol derivative and absorbed into the
circulatory system.
The more pigment there is in the skin, the less of the vitamin
is produced. Vitamin D is involved in cell reproduction, blood
cell formation, and enhances the immune system. It is needed for
regulating glucose. Dietary sources of vitamin D are egg yolks,
butter, fortified milk, and fish livers or oil. After
absorption, vitamin D is transported to the liver for storage
and deposits are found in the skin, brain, spleen, and bones.
Excessive amounts may cause a rise of calcium and phosphorus in
the blood and excessive excretion
of calcium in the urine. This may lead to calcification of soft
tissues and of the walls of the blood vessels and kidney
tubules, a condition called hypercalcemia. Too much vitamin D
for prolonged periods can result in weight loss, headaches, and
kidney stones.
Vitamin E
Vitamin E plays an essential role in cellular respiration of
all muscles. This makes it possible for muscles and their nerves
to function with less oxygen, thereby increasing endurance and
stamina.
Studies have shown that vitamin E can reduce the stickiness of
blood preventing its tendency to form blood clots. It also acts
as a powerful antioxidant and protects LDL cholesterol from
oxidation. Recent studies have shown vitamin E supplementation
of 100 IU daily for 2 years reduced the risk of heart attack3
and in another, 400 to 800 IU daily produced a 77% drop in
nonfatal heart attacks.4 The d-alpha form of supplemental E is
natural and more effective than the synthetic dl form. The gamma
tocopherol
may better protect against oxidation and supplements should
include the mixed tocopherols.
In animal studies, rats were exposed to ozone levels that are
normally found in industrial areas. Ozone is a single reactive
oxygen molecule that does much injury to cellular structures.
Those that received little of the vitamin had the most damage,
those given larger doses essentially had no damage. Tissue
damage can also occur from the diet; the same reactive oxygen
molecules are present when unsaturated vegetable oils are
exposed to air and heat and become rancid. The antioxidant
properties of vitamin E may retard the aging process. Topically
the vitamin can reduce scar formation (applied after the wound
has closed) from burns, surgery, or other injuries.
Vitamin E is a fat-soluble vitamin, absorbed in the presence of
bile salts and fat. From the intestine, it is absorbed into the
lymph and transported in the bloodstream as tocopherol to the
liver where high concentrations are stored. It is also stored in
the fatty tissues, heart, muscles, testes, uterus, blood, and
adrenal and pituitary glands. The vitamin is one of a group of
compounds called tocopherols which include beta, delta, epsilon,
gamma, and zeta. Vitamin E is mainly found in the oily portions
of foods like whole grains and seeds. The milling process
reduces vitamin E content by as much as 85%. The vitamin has a
tendency to raise blood pressure if given in supplemental form,
therefore, initial intake should be low and gradually increased.
High doses can interfere with iron metabolism; at dosages of 300
to 400 IU a day, nausea, intestinal distress, fatigue, weakness,
and urinary abnormalities may be experienced in some
individuals.
Vitamin K
Vitamin K is necessary for the formation of prothrombin, a chemical required in blood clotting. It is also involved in a body process, phosphorylation, in which phosphate, when combined with glucose, passes through the cell membranes and is converted into glycogen. It is involved in bone formation by transporting calcium. The vitamin is absorbed in the upper intestinal tract with the aid of bile salts, transported to the liver and stored in small quantities. Besides dietary sources, it is manufactured in the intestinal tract by certain bacteria. Synthetic vitamin K can be toxic. Supplemental vitamin K can interfere with the actions of some blood thinners.
Minerals
Calcium
Calcium is the most abundant mineral in the body.
Ninety-eight percent is found in the bones, 1% in teeth, and 1%
in other tissues. When the body is at rest, calcium is pulled
out of the bones to be used elsewhere, establishing the
importance of daily adequate intake of the mineral and of
exercise. Calcium helps regulate nerve transmissions and along
with magnesium, is important for cardiovascular health. If
muscles do not have enough calcium, they cannot contract or if
contracted, do not relax, which results in cramps.
The mineral is good for relaxation and improves the quality of
sleep. During the hormonal shifts of menopause, the dominance of
the parathyroid hormone causes calcium to be removed from bone
resulting in osteoporosis. Requirements for calcium may vary
depending on how much each individual absorbs and retains.
Pregnant women need to ingest at least 1200 mg a day, especially
in the last two months because over half of the calcium in an
infants body is deposited at that time. Moderate amounts of
protein, lactose, and butterfat enhance absorption of calcium,
therefore, low-fat rather than nonfat milk products should be
part of the diet, especially for children.
Excess protein in the diet causes a urinary loss of calcium.
High intakes of calcium interfere with the absorption of other
minerals including iron, zinc, and manganese, disrupt the
functioning of the nervous and muscular systems, and may prevent
blood coagulation.
Chromium
A trace element, chromium is essential in producing a
substance called glucose tolerance factor (GTF) which is
important in the utilization of insulin, a hormone that
stabilizes blood sugar levels. The mineral is also involved in
the synthesis of fatty acids and cholesterol. Eating refined
sugar can cause depletion of body chromium as sugar lacks
sufficient amounts of the mineral for its own digestion. The
chromium content of refined sugar is 0.02 parts per million (ppm)
whereas the by-product, molasses, has 0.2 ppm;
sugar cane juice has approximately 0.1 ppm.
Copper
Copper assists in the formation of hemoglobin and red blood
cells by facilitating the absorption of iron and may protect
against atherosclerosis. Iron metabolism depends on copper. Zinc
and copper have similar elemental properties and have a
balancing effect on each other. Both are related to the
functioning of the nervous system and compete in the intestinal
tract for absorption. Excess zinc supplementation affects the
absorption of copper. Too much vitamin C can impair its
metabolism. Copper is a component of superoxide dismutase (SOD),
an antioxidant enzyme; and it is necessary for the production of
ATP, adenosine triphosphate, the body’s energy source. Synthesis
of collagen, certain hormones, and enzymes depend on copper.
High levels of copper may aggravate PMS and it can be increased
by the use of birth control pills. Excess copper can cause
mental and emotional problems and may be prominent in
schizophrenia. Anemia not helped by iron may be an indication of
elevated copper levels.
Serum copper, elevated by estrogens, rises progressively during pregnancy
and takes several months to return to normal after delivery,
during which time the mineral could be a factor in the
depression and psychosis women often experience right after
giving birth. Excess copper may be getting into the diet from
contaminated food and water and copper pipes through which
drinking water flows.
Iodine
Iodine aids in the development and functioning of the thyroid gland and is an integral part of thyroxine, a principal hormone produced by the thyroid gland. Thyroid hormones are important for normal cellular metabolism. Sea plants and animals absorb iodine from seawater and are good sources of the mineral.
Iron
At the center of a hemoglobin molecule is iron and when
combined with oxygen, it gives arterial blood its bright red
color. Hemoglobin transports oxygen in the blood from the lungs
to the tissues which need oxygen to maintain basic life
functions. Iron is also necessary for the formation of myoglobin,
found only in muscle tissue, which supplies oxygen to the muscle
cells.
Significant amounts of iron can be lost during menstruation and
needs are higher for pregnant women. Protein and vitamin C aid
in the absorption of iron by chelating or attaching onto the
iron ion and carrying it across the intestinal walls. Excess
iron can accumulate in the body to toxic levels. Take iron
supplements only on the advice of a physician.
Magnesium
Along with calcium, magnesium is found in bones and is
important in the conduction of electrical impulses of the
muscles and nerves. Magnesium, like calcium, is a relaxant yet
either one in excess
causes a malfunction of the nervous system. Keeping both
minerals in balance is important. Most magnesium is found in the
cell where it activates the enzymes necessary for the metabolism
of carbohydrates and amino acids. It is involved in insulin
secretion and function. Magnesium has been shown to reduce
hyperactivity in children who had low magnesium levels. It may
improve vision in glaucoma patients, lower blood pressure, and
may be a factor in chronic fatigue syndrome. The mineral is
refined out of many foods and amounts are lost during cooking of
foods.
Manganese
Manganese plays a role in activating numerous enzymes and in
skeletal development involving
connective tissue which provides the framework for bone and its
growth. Along with zinc, the mineral lowers serum copper levels
and balances histamine levels, a substance that is released
during allergic reaction. Manganese stimulates activity of the
antioxidant enzyme SOD, or superoxide dismutase, and helps
maintain glucose levels.
Potassium and sodium
Potassium and sodium exist in important ratios, potassium
concentrated inside the cell and sodium remaining outside. They
regulate water balance in the body and their equilibrium enables
them to
stimulate nerve impulses for the heart and other muscle
contractions. Depletion of either element
would depress cell response. The typical American diet of
processed and convenience foods do not contain sufficient
amounts of potassium creating an imbalance between the two
minerals.
Diuretics can cause an excessive urinary loss of
potassium. An excess of sodium is related to high
blood pressure and fluid retention which taxes the heart and
kidneys.
Selenium
Selenium is a natural antioxidant and appears to preserve the
elasticity of tissues by delaying oxidation
of polyunsaturated fatty acids. It supports the immune system,
protects against cancer, is a factor in fertility, and is
necessary for the production of prostaglandin, a substance that
affects blood pressure.
Selenium content of foods depends on the extent of its presence
in soil whether directly as plant food or indirectly as animal
products when selenium levels are derived from feed. Sulfur
content in commercial fertilizers inhibits plant absorption of
the mineral. Refining, processing, and cooking of foods reduce
selenium levels. High doses are toxic and no more than 300 mcg a
day are recommended.
Zinc
Zinc is a constituent of at least 25 enzymes involved in
digestion and metabolism. It is a component of insulin and
essential in the synthesis of nucleic acids which control the
formation of different proteins in the cell. Zinc is important
for the proper development of the reproductive organs and normal
functioning of the prostate gland. The mineral speeds the
healing of wounds and bone fractures, keeps the skin healthy,
and is involved in the formation of keratin, a substance in hair
and nails. It supports the immune system and protects against
free radicals.
Zinc content of foods depends on soil content. Chemical
fertilizers impair its absorption intoplants. The milling
process removes substantial amounts of the mineral. Although
moderate doses enhance immunity, excessive amounts depress it.
It is recommended that no more than 100 mg be taken daily.
Water
Respiration, digestion, assimilation, metabolism,
elimination, waste removal, and temperature regulation are
bodily functions that can only be accomplished in the presence
of water. Water is essential in dissolving and transporting
nutrients such as oxygen and mineral salts via the blood, lymph,
and other bodily fluids. Water also keeps the pressure, acidity,
and composition of all chemical reactions in equilibrium.
Only oxygen is more essential than water in sustaining the life
of all organisms. Human beings can live around 5 weeks without
protein, carbohydrates, and fats but just 5 days without water
in a moderate climate. Its circulation between the blood and
bodily organs is perpetual and always maintained in proper
balance; however, a certain amount is eliminated daily through
evaporation or excretion and must be replaced. Most of this
water is removed by the kidneys, through which the entire blood
supply passes and is filtered 15 times each hour. Whenever the
body becomes overheated, two million sweat glands excrete
perspiration which is 99% water. The heat of the blood
evaporates the sweat, cooling the body and keeping the internal
organs at a constant temperature. A minimal but consistent loss
of water occurs during the processes of breathing and tearing.
Moisture is breathed out from the water-lined nasal passages and
the lungs. Dry air draws off more water than humid air. Tiny
tear ducts carry a liquid solution to the upper eyelids, which
lubricate the eyes 25 times every minute. The tears then pass
down to the nose where they evaporate.
To replace lost water, approximately 3 qt is needed by the body
each day under normal conditions. More strenuous activity, a
high climate temperature or a diet too high in salt may increase
this requirement. The sense of thirst is controlled by a part of
the forebrain called the hypothalamus. Metabolic water is
produced as a by-product of the food combustion process yielding
as much as a pint per day. Foods can provide up to 11⁄2 qt. For
example, fruits and vegetables are more than 90% distilled
water. Even dry
foods like bread and crackers are 35 and 5% water, respectively.
Drinking water is the other source of replenishment. Municipal
water treatment systems are mainly concerned with disinfection
and do not remove most chemicals. Because of environmental
pollution,
there is probably not a water source that is not contaminated to
some degree. The most efficient removal and reduction of the
widest range of contaminants is in bottled water, purified by
ozone, reverse osmosis, and distillation, or a combination.
Needed minerals do not have to be obtained from drinking water
as they are found in a wide range of foods in a varied and
wholesome diet.